A single session of hyperbaric oxygen therapy demonstrates acute and long-lasting neuroplasticity effects in humans: a replicated, randomized controlled clinical trial.

Primary outcome (secondary hyperalgesia areas) Baseline data Data consistency during Session 1 vs Session 2 ( Figure 2B ) was examined by ICC’s (0.85 [0.64–0.94]) and by comparisons of baseline assessments using simple paired sample tests demonstrating a highly significant difference in baseline assessments between the sessions (Wilcoxon: P =0.0017).

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