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Smoking habits and incidence of cardiovascular diseases in men and women: findings of a 12 year follow up among an urban Eastern-Mediterranean population.

BMC Public Health · 2019 · PMC6683328 · PMID 31382950

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an increasing trendno p-value reported
Regarding the high prevalence and incidence of CVDs, there has been an increasing trend to ascertain the main determinants and underlying causes of these diseases.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.