Barely Significant
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A 12-year trend analysis of the incidence of gastrointestinal cancers in East Azerbaijan: last updated results of an ongoing population-based cancer registry.

BMC Cancer · 2019 · PMC6686571 · PMID 31391032

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a decreasing trendno p-value reported
Esophageal cancer There was a decreasing trend in the ASRs of esophageal cancer in both sexes, giving an overall APC of − 3% (95% CI: − 6.1 to 0.2).

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a slightly increasing trendno p-value reported
In men, there was a decreasing trend of − 14.5% (95% CI: − 54.6 to 60.8) between 2004 and 2006, then a slightly increasing trend in the mid Joinpoint (2006–2013; APC, 4.4; 95% CI: − 6.4 to 16.5), and a significant increase of 139.9% (95% CI: 62.4 to 254.2; P ≤ 0.05) between 2013 and 2015.

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an increasing trendno p-value reported
In women, we observed an increasing trend at the first Joinpoint, with an APC of 18.7% (2004–2010), before seeing a slight decrease (− 3.4%) in the APC between 2010 and 2013, and a further increase of 18.6% in the last 3 years (2013–2015).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.