Saturation mutagenesis of twenty disease-associated regulatory elements at single base-pair resolution.

Nat Commun · 2019 · PMC6687891 · PMID 31395865

Europe PMC DOI

hedged sentence

0.0000

closest p · 0.0× alpha

0.0000

boldest claim

The sentences

highly significantp -value < 10 −11actually significant

The PWM score changes are highly significant between activating and repressing variants (one-sided Wilcoxon Rank Sum test, p -value < 10 −11 ).

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.