Effect of the inhaled PDE4 inhibitor CHF6001 on biomarkers of inflammation in COPD.

Respir Res · 2019 · PMC6688371 · PMID 31399091

Europe PMC DOI

hedged sentence

0.0570

closest p · 1.1× alpha

0.0570

boldest claim

The sentences

almost significantp = 0.057so close (0.05 < p ≤ 0.1)

CHF6001 1600 μg significantly decreased TNFα ex-vivo (i.e., assessed after incubation of whole blood with lipopolysaccharide); the decrease with CHF6001 800 μg was almost significant ( p = 0.057).

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