Changing indications and surgical techniques for keratoplasty during a 16-year period (2003-2018) at a tertiary referral hospital in Japan.

Clin Ophthalmol · 2019 · PMC6689759 · PMID 31496641

Europe PMC DOI

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a decreasing trendno p-value reported

Failed PK and failed DSAEK were increasing linearly in the beginning and reached a plateau followed by a decreasing trend.

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an increasing trendno p-value reported

Perforation was increasing in the beginning, reached a plateau around 2009, and then showed an increasing trend in the last part of study period.

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a slightly increasing trendno p-value reported

The proportion of PK procedures decreased significantly in the beginning and showed a slightly increasing trend after a plateau around 2015.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.