Vitamin D reverts resistance to the mTOR inhibitor everolimus in hepatocellular carcinoma through the activation of a miR-375/oncogenes circuit.

Sci Rep · 2019 · PMC6690984 · PMID 31406139

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an obvious trendno p-value reported

On the other hand, in HepG2 EveR cells, a relevant increase in messenger and protein VDR expression, despite an obvious trend in cell resistance after EVE treatment, did not correspond to a significant increase in EVE sensitivity; therefore, HepG2 EveR cell line was not considered to assess the role of VitD in condition of EVE resistance.

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