Additionally, our results were not limited to neuroblastoma cells, but were also observed in other cancer cell lines like colon cancer or leukemia cells ( Figure 5 C and 5 D ) and also exerted a highly significant in vivo effect in a xenograft transplantation mouse model.
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Modulation of Respiration and Mitochondrial Dynamics by SMAC-Mimetics for Combination Therapy in Chemoresistant Cancer.
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