Decoding cancer heterogeneity: studying patient-specific signaling signatures towards personalized cancer therapy.

This result is highly significant from two aspects: (1) It is in line with the high degree of inter-tumor heterogeneity that is known to exist among tumors. 17 unbalanced processes can be assembled into thousands of unique barcodes comprising 1-4 active processes; (2) Our findings suggest that the cohort of patients consists of 452 types of cancer, rather than only 11 types.

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