Cytotoxic Granule Exocytosis From Human Cytotoxic T Lymphocytes Is Mediated by VAMP7.

Importantly, in both cases we found a highly significant co-localization of VAMP7 with the CG marker proteins at any time point measured, with Pearson's coefficients of correlation of 0.58 ± 0.03 (5 min), 0.59 ± 0.03 (10 min), and 0.60 ± 0.02 (15 min) for granzyme B ( Figure 3B ) and 0.46 ± 0.03 (5 min), 0.49 ± 0.03 (10 min), and 0.52 ± 0.03 (15 min) for perforin ( Figure 3C ), respectively.

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