MDMA-assisted psychotherapy for treatment of PTSD: study design and rationale for phase 3 trials based on pooled analysis of six phase 2 randomized controlled trials.

Psychopharmacology (Berl) · 2019 · PMC6695343 · PMID 31065731

Europe PMC DOI

hedged sentence

0.0530

closest p · 1.1× alpha

0.0530

boldest claim

The sentences

trending toward significanceP = 0.053so close (0.05 < p ≤ 0.1)

Depression symptom improvement on the BDI-II was greatest for the active dose group, estimated mean (SE) change active − 12.4 (1.84) versus control group − 6.5 (2.69), with the difference between groups trending toward significance [ t (61) = − 1.97, P = 0.053].

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