Coexisting Molecular Determinants of Acquired Oxaliplatin Resistance in Human Colorectal and Ovarian Cancer Cell Lines.

Int J Mol Sci · 2019 · PMC6696456 · PMID 31344863

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highly significantno p-value reported

Role of BCRA1 in DNA Damage Response Less frequently observed yet highly significant for the drug-resistant variants of LoVo-Li is the role of BCRA1 in DNA damage response, metabolism of xenobiotics by cytochrome p450, xenobiotic metabolism signaling pathways, and G1/S checkpoint regulation.

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