Barely Significant
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Comparative effectiveness of antiepileptic drugs in juvenile myoclonic epilepsy.

Epilepsia Open · 2019 · PMC6698679 · PMID 31440723

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a decreasing trendno p-value reported
an increasing trendno p-value reported
The relative frequency of valproate trials shows a decreasing trend since 2003 while there is an increasing trend for levetiracetam.

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