Plasma Inter-Alpha-Trypsin Inhibitor Heavy Chains H3 and H4 Serve as Novel Diagnostic Biomarkers in Human Colorectal Cancer.

Dis Markers · 2019 · PMC6701429 · PMID 31481982

Europe PMC DOI

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highly significantno p-value reported

The NRI analysis showed the range from 6.2% to 17.1% for CRC detective improvement when adding ITIH 3 and/or ITIH 4 to TIMP-1, compared with TIMP-1 alone, indicating the highly significant effects of ITIH 3 and/or ITIH 4 on diagnosis accuracy improvement.

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