Optimising computerised decision support to transform medication safety and reduce prescriber burden: study protocol for a mixed-methods evaluation of drug-drug interaction alerts.

5 This is a highly significant problem for patients in hospital, who take on average 12 medications. 6 7 Studies of DDI rates in hospitals report highly variable results, with the rate of DDIs dependent on how they are defined (eg, ‘potential DDI’ vs ‘actual DDI’), measured (eg, per patient, per order) and identified (eg, via chart review vs automatic detection using software).

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