Evaluation of the safety of using propofol for paediatric procedural sedation: A systematic review and meta-analysis.

A marginally significant risk reduction was observed overall when propofol was used (RD = −0.03 [−0.06, 0.01], I 2 = 55.3%) (Supplementary Fig.

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Twenty-two studies with 27 comparisons provided information on respiratory complications, and there was an overall trend towards an increased risk of respiratory adverse events when propofol was used (Supplementary Fig.

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