Sex and age specific reduction in stress resistance and mitochondrial DNA copy number in Drosophila melanogaster.

For heat resistance (CTmax), males became less tolerant with increasing age as we observed a significant negative slope with age in the regression (p = 7.91e-23), whereas for females, their resistance to heat is not changed with age suggested by the highly significant positive interaction effect (p = 1.20e-12) (Table 1 , Fig. 1B ).

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