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A prospective randomized trial of povidone-iodine suppository before transrectal ultrasonography-guided prostate biopsy.

Medicine (Baltimore) · 2019 · PMC6708823 · PMID 30896629

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an increasing trendno p-value reported
As active surveillance for patients with low Gleason scores and prostate-specific antigen (PSA) levels shows an increasing trend, the incidence of transrectal prostate biopsy is expanding even more.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.