They 37 concluded that the multivariate analysis revealed that the use of GnRHa during therapy is a “strong, independent, and highly significant predictor of pregnancies.” In our own research, we found that GnRHa co-treatment, along with chemotherapy, could significantly increase natural conceptions in survivors ( P < 0.006 ), in addition to preserving COF (OR = 6.87) in a large group of young women followed for more than 2 decades. 19 Nine
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Fertility Preservation Using GnRH Agonists: Rationale, Possible Mechanisms, and Explanation of Controversy.
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