miRNA profile obtained by next‑generation sequencing in metastatic breast cancer patients is able to predict the response to systemic treatments.

Int J Mol Med · 2019 · PMC6713405 · PMID 31364724

Europe PMC DOI

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0.0550

closest p · 1.1× alpha

0.1000

boldest claim

The sentences

close to being significantP=0.055so close (0.05 < p ≤ 0.1)

The results revealed that 6 miRNAs exhibited significant differences between the 2 groups (P<0.05) (miR-4485-3p, miR-1273a, miR-342-3p, miR-200c-3p, miR-200b-3p and miR-187-3p) and 1 miRNA was close to being significant (miR-301a-3p, P=0.055) ( Table SI ). miRNAs with clinical significance To assess the clinical significance of the miRNA panel, we applied the non-parametric Mann-Whitney U test using clinical variables ( Table II ).

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borderline significantP<0.1so close (0.05 < p ≤ 0.1)

Statistically significant and borderline significant variables (P<0.1) were included in multivariate logistic regression analysis.

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