The adhesion-GPCR BAI1 shapes dendritic arbors via Bcr-mediated RhoA activation causing late growth arrest.

Did the authors attempt to perform this experiment in vivo? It would be highly significant, if possible, to show whether electroporating tdTomato-Cre into RhoA flox/flox mice at E18 would lead to a similar BAI1-mediated dendritic overgrowth phenotype at P21 as shown in Figure 1. 4) Do the mutations the authors make in BAI1 affect the surface localization of the protein?

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