Evidence from routine clinical practice: EMPRISE provides a new perspective on CVOTs.

Cardiovasc Diabetol · 2019 · PMC6717330 · PMID 31472683

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narrowly missed statistical significanceno p-value reported

More recently, the CREDENCE study, in which the majority of patients had reduced renal function, showed that canagliflozin narrowly missed statistical significance for reducing CV death even in this at-risk group of patients [ 23 ].

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