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Conditioned media from dental pulp stem cells improved diabetic polyneuropathy through anti-inflammatory, neuroprotective and angiogenic actions: Cell-free regenerative medicine for diabetic polyneuropathy.

J Diabetes Investig · 2019 · PMC6717901 · PMID 30892819

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an increasing trendno p-value reported
An increasing trend of expression of the pro‐inflammatory gene, TNF‐α, was also seen in the sciatic nerves of diabetic rats, although this increase was not significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.