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Review of current diagnostic methods and advances in <i>Helicobacter pylori</i> diagnostics in the era of next generation sequencing.

World J Gastroenterol · 2019 · PMC6718044 · PMID 31528091

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an increasing trendno p-value reported
Also in Europe, an increasing trend of clarithromycin resistance in H. pylori can be observed with an overall primary clarithromycin resistance rate of 17%[ 34 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.