Development and analytical validation of a next-generation sequencing based microsatellite instability (MSI) assay.

Stringent filtering was further applied, where, unique homopolymer indels (alt allele length range 5–7 bp) with very highly significant fisher’s exact test P value < 0.0001 that were present in ≥ 80% (at least 6 out of 7) MSI-H cases but not in MSS cases were identified.

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