Barely Significant
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Effectiveness of intravenous acetaminophen for postoperative pain management in shoulder arthroplasties: A population-based study.

J Orthop Translat · 2019 · PMC6718947 · PMID 31508315

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a nonsignificant trendno p-value reported
similarly found no difference in the daily morphine equivalent use or LOS between IV APAP and control groups of patients undergoing TKA and even saw a nonsignificant trend towards increased opioid use in the IV APAP group [16] .

also in 5,406 other papers

a decreasing trendno p-value reported
The overall median opioid utilization (in OME) showed a decreasing trend with no differences in patients receiving IV APAP versus those who did not ( Fig. 1 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.