SNX3 drives maturation of <i>Borrelia</i> phagosomes by forming a hub for PI(3)P, Rab5a, and galectin-9.

J Cell Biol · 2019 · PMC6719455 · PMID 31337623

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Depletion of SNX1 led to a slight and not significant reduction of 15% of compaction (60.1% ± 10.4% compaction for SNX1 siRNA–treated cells compared with 70.4% ± 6.2% for controls), while depletion of SNX3 led to a pronounced and highly significant reduction of 61% (27.7% ± 5.3% compaction).

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