Statistical analysis allowed the screening out of Differentially Expression Genes (DEGs) that exhibited highly significant differences according to the following criteria: DEGs increased in PLC/PRF5-Notch1 versus control group and simultaneously decreased in HCCLM6-shNotch1 versus shcontrol group; and vice versa, the expression of DEGs reduced in PLC/PRF5-Notch1 versus control group and simultaneously increased in HCCLM6-shNotch1 and shcontrol group.
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An essential role of RNF187 in Notch1 mediated metastasis of hepatocellular carcinoma.
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