A Pilot Phase 1 Study of Intrathecal Pemetrexed for Refractory Leptomeningeal Metastases From Non-small-cell Lung Cancer.

Front Oncol · 2019 · PMC6730526 · PMID 31544065

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a decreasing trendno p-value reported

The drug concentration showed a decreasing trend in serial CSF samples following each IP.

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