Optimization of quercetin extraction method in <i>Dendrobium officinale</i> by response surface methodology.

At the same time, the first term A, the interaction terms AB and AC, and the second terms A 2 , B 2 , and C 2 showed extremely significant performance, while the first terms B and C also showed significant performance. 2.8.2 Interaction effects of different experimental factors on response variables Response surface images of three-dimensional surface maps consisting of the ethanol concentration (A), solid-to-liquid ratio (B) and ultrasonic power (C) illustrate the pairwise interactions between the factors [31] .

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When the solid-to-liquid ratio was more than 1:50 g/mL, the extracted amount of quercetin was no longer significantly increased, butexhibit a decreasing trend.

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