Barely Significant
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Histamine and migraine revisited: mechanisms and possible drug targets.

J Headache Pain · 2019 · PMC6734463 · PMID 30909864

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a positive trendno p-value reported
Cyproheptadine and methdilazine showed only a positive trend [ 21 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.