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Biochemical parameters of rickets in Iranian children: A systematic review and meta-analysis.

J Res Med Sci · 2019 · PMC6734666 · PMID 31523262

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an increasing trendno p-value reported
This indicated an increasing trend in the biochemical symptoms of rickets from 1975 to 2018.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.