This confirmed a strong and highly significant tryptase-induced downregulation of SNORA83 and EGR1 (Fig. 7a ), as well as a significant downregulation of SNORA55 and RNU4–2, and a significant upregulation of MIR16–2 (Fig. 7b ).
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Exosome-mediated uptake of mast cell tryptase into the nucleus of melanoma cells: a novel axis for regulating tumor cell proliferation and gene expression.
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