Proton pump inhibitor use increases mortality and hepatic decompensation in liver cirrhosis.

There was a trend towards significance among patients with viral hepatitis aetiology [aHR 3.23, (0.99-10.52); P = 0.052], ascites [aHR 1.91, (0.96-3.78); P = 0.063], and those without prior decompensation at baseline [aHR 1.99, (0.98-4.00); P = 0.057] ( Supplementary Table 3 ).

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