Exosome reporter mice reveal the involvement of exosomes in mediating neuron to astroglia communication in the CNS.

Nat Commun · 2019 · PMC6742670 · PMID 31515491

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highly significantno p-value reported

Given the high abundance of GLT1 in the CNS with multiple regulatory mechanisms and > 50% reduction of GLT1-dependent glutamate uptake is more commonly observed in pathological conditions 39 , we consider a 30% reduction of glutamate uptake by exosome blockade highly significant.

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