highly significantp < 0.001
Rph3A+ spines exhibit a highly significant increased spine head area (***p < 0.001; Figures 1 C and 1D and Table 1 ) and PSD length (***p < 0.001; Figures 1 E and 1F and Table 1 ) and also an augmented PSD thickness (*p < 0.05; Figures 1 G and 1H and Table 1 ) compared to Rph3A− ones, thus defining a selective accumulation of the protein in more “mature” synapses.