Bruton's Tyrosine Kinase Inhibition Attenuates the Cardiac Dysfunction Caused by Cecal Ligation and Puncture in Mice.

Front Immunol · 2019 · PMC6743418 · PMID 31552054

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highly significantno p-value reported

We found a highly significant negative correlation between the degree of BTK and PLCγ activation and the decline in EF, strongly suggesting that BTK activation drives or precedes the cardiac dysfunction associated with sepsis.

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