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Leprosy in elderly people and the profile of a retrospective cohort in an endemic region of the Brazilian Amazon.

PLoS Negl Trop Dis · 2019 · PMC6743788 · PMID 31479442

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a decreasing trendno p-value reported
Discussion The leprosy detection rate per 10 thousand inhabitants in the general population of the state of Pará showed a decreasing trend throughout the years.

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an increasing trendno p-value reported
There was an increasing trend between 2010 and 2012.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.