SLC39A8 gene encoding a metal ion transporter: discovery and bench to bedside.

Hum Genomics · 2019 · PMC6744627 · PMID 31521203

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

0.0000

boldest claim

The sentences

somewhat significantP = 2.7 × 10 −6actually significant

SLC39A8 and the central nervous system Another early GWAS discovery of a SLC39A8 variant involved a case-control study of 476 schizophrenia patients and 447 control subjects from Galicia, combined with a replication sample comprising >4000 cases and >15,100 control subjects of European origin ; the SNV (rs13107325; p.Ala391Thr) was somewhat significant ( P = 2.7 × 10 −6 ) in the collective sample, following Bonferroni correction [ 60 ].

also in 217 other papers

highly significantno p-value reported

In the transcriptomics analysis of the Slc39a8 ( neo / neo ) knockdown mouse [ 28 ], kidney exhibited highly significant upregulation of Npr3 (natriuretic peptide receptor-3).

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.