Positive selection in dNTPase SAMHD1 throughout mammalian evolution.

Proc Natl Acad Sci U S A · 2019 · PMC6744909 · PMID 31451672

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hedged sentence

0.0000

closest p · 0.0× alpha

0.0000

boldest claim

The sentences

highly significantP < 10 −6actually significant

By calculating the probability that 11 of 36 identified sites should fall in this binding region comprising 20 sites of a total 626 sites by chance ( Methods ), we found the concentration of sites identified as under positive selection in this region to be highly significant ( P < 10 −6 ).

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