Diagnostic and Prognostic Role of Blood and Cerebrospinal Fluid and Blood Neurofilaments in Amyotrophic Lateral Sclerosis: A Review of the Literature.

Despite a considerable variability, they showed an increasing trend of plasma p-NfH over time, which was inversely correlated with survival length: patients with rapidly progressive disease and shorter survival present higher p-NfH levels early, followed by a fall later in the disease, while lower levels have been observed in slower progressors.

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