<i>In vivo</i> Bioluminescence Imaging Used to Monitor Disease Activity and Therapeutic Response in a Mouse Model of Tauopathy.

Front Aging Neurosci · 2019 · PMC6751306 · PMID 31572168

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fell just short of statistical significanceno p-value reported

Similarly knockout of the TREM2 receptor in P301S mice caused a reduction of microgliosis, astrogliosis and neurodegeneration (although the reduction of hippocampal tau phosphorylation in this study fell just short of statistical significance; Leyns et al., 2017 ).

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