Genetic determinants of cellular addiction to DNA polymerase theta.

Nat Commun · 2019 · PMC6753077 · PMID 31537809

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highly significantno p-value reported

We also observed highly significant synthetic sickness between Polq deficiency and all four components of the 53BP1 anti-resection pathway included in our screen ( 53bp1 , Paxip1 , Mad2l2 , and Rif1 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.