The Highly Pure Neem Leaf Extract, SCNE, Inhibits Tumorigenesis in Oral Squamous Cell Carcinoma via Disruption of Pro-tumor Inflammatory Cytokines and Cell Signaling.

In the SCC4 cell line, MMP9 was drastically reduced by SCNE and NIM at all concentrations tested, with reductions in MMP2 that were not significantly significant ( Figure 3C and Supplemental Figure 1 ).

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