Differences in DNA Methylation Between Disease-Resistant and Disease-Susceptible Chinese Tongue Sole (<i>Cynoglossus semilaevis</i>) Families.

All of the former 27 CpG sites except CpG2 and CpG23 possessed highly significant discrepancies in MLs between the DR-CS and DS-CS families ( P < 0.05) ( Figure 4A ).

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The two families used in this study were derived from a long-term selection, and there may be significant differences in other phenotypic traits besides the disease resistance trait, such as fatty acid metabolism, skin color variations, thermal acclimation, and sex ratio.

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