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SCF promotes the production of IL-13 via the MEK-ERK-CREB signaling pathway in mast cells.

Exp Ther Med · 2019 · PMC6755428 · PMID 31555361

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an increasing trendno p-value reported
Epidemiological studies have shown that there is an increasing trend in all parts of the world (including China) about the morbidity and mortality of asthma ( 24 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.