Barely Significant
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Nicorandil effects on platelet function, Hs-CRP, MMP-9 and myocardial antioxidation in patients with unstable angina.

Exp Ther Med · 2019 · PMC6755476 · PMID 31572549

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an increasing trendno p-value reported
In recent years, with the increase of social pressure on middle-aged people and the increase of aging population, the incidence rate of unstable angina has also shown an increasing trend year by year.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.