The nature of ligand efficiency.

J Cheminform · 2019 · PMC6755556 · PMID 30706294

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a weak trendno p-value reported

Affinity (or potency) should always be plotted as a function of molecular size during the course of an F2L project and even a weak trend can be used to normalize data.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.