Novel roles of ER stress in repressing neural activity and seizures through Mdm2- and p53-dependent protein translation.

PLoS Genet · 2019 · PMC6762060 · PMID 31557161

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a slight trendno p-value reported

These results of p53 ubiquitination were consistent with the total protein level of p53, where a significant reduction of p53 was seen in Mdm2 f/+ - Emx1 -Cre- cultures but a slight trend toward elevation of p53 was seen in Mdm2 f/+ - Emx1 -Cre+ cultures after Tg treatments ( Fig 4D ).

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