The current study found that the lactate dehydrogenase activity and urea level were surprisingly the highest in the goalie/substitute group, compared with the midfielder/defender group, and a decreasing trend of the levels of these variables over time was noticed in these groups (a significant negative correlation of LDH and urea with match-time for the season).
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The sentences
The most active players, like midfielders, perform immense physical effort during each soccer match, so it is therefore not surprising that an increasing trend in the CK level was observed in this subgroup.